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| Craig Horbinski, MD, PhD. |
The illustrious Craig Horbinski, MD, PhD wrote in to share a link to an online tool which his team developed which helps triage brain tumor cases that might benefit from additional molecular testing. Here's what the University of Kentucky neuropathologist had to say about this new website: "We have developed an online-based tool to
provide a statistical estimate of the likelihood of an IDH1/2 mutation
in a glioma, based
on a few easily-obtained parameters.
Several variables like patient age, WHO grade, etc. are well-known to
correlate with mutations, but no formula has yet been developed that
synthesizes those variables into one unified probability score. An added
feature is that it generates separate scores
if no testing has been done at all, and if R132H IDH1 immunostain was
done but is negative. Hopefully this will help pathologists and
investigators better triage cases that would benefit from additional
testing, both in clinical and in research endeavors."
Thanks, Craig!
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